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Table 1 One-way ANOVA test between serotonin (ng/100 mg), IFN-γ (pg/100 mg) and GST (μmol/min/100 mg) in control, PPA-intoxicated and NAC protected and treated rats

From: Protective and therapeutic potency of N-acetyl-cysteine on propionic acid-induced biochemical autistic features in rats

Parameters Groups Min Max Mean ± SD P value
Serotonin (ng/100 mg) Control 3.41 4.80 4.12 ± 0.51 0.001
PPA 2.32 3.03 2.76 ± 0.29 a
NAC protective 3.12 3.94 3.53 ± 0.27 a
NAC therapeutic 2.58 3.25 2.94 ± 0.27 a
IFN-γ (pg/100 mg) Control 88.27 115.64 99.91 ± 8.84 0.001
PPA 177.34 194.59 184.72 ± 6.24 a
NAC protective 149.07 163.59 156.99 ± 5.23 a
NAC therapeutic 160.57 171.66 167.60 ± 4.01 a
GST (μmol/min/100 mg) Control 0.78 0.95 0.85 ± 0.06 0.001
PPA 0.44 0.55 0.50 ± 0.04 a
NAC protective 0.62 0.77 0.69 ± 0.05 a
NAC therapeutic 0.59 0.70 0.65 ± 0.04 a
  1. Significant levels between the three groups are illustrated as superscript letters when P <0.05.