Table 1 One-way ANOVA test between serotonin (ng/100 mg), IFN-γ (pg/100 mg) and GST (μmol/min/100 mg) in control, PPA-intoxicated and NAC protected and treated rats

Serotonin (ng/100 mg)

Control

3.41

4.80

4.12 ± 0.51

0.001

PPA

2.32

3.03

2.76 ± 0.29 ^a

NAC protective

3.12

3.94

3.53 ± 0.27 ^a

NAC therapeutic

2.58

3.25

2.94 ± 0.27 ^a

IFN-γ (pg/100 mg)

Control

88.27

115.64

99.91 ± 8.84

0.001

PPA

177.34

194.59

184.72 ± 6.24 ^a

NAC protective

149.07

163.59

156.99 ± 5.23 ^a

NAC therapeutic

160.57

171.66

167.60 ± 4.01 ^a

GST (μmol/min/100 mg)

Control

0.78

0.95

0.85 ± 0.06

0.001

PPA

0.44

0.55

0.50 ± 0.04 ^a

NAC protective

0.62

0.77

0.69 ± 0.05 ^a

NAC therapeutic

0.59

0.70

0.65 ± 0.04 ^a