Skip to main content
Figure 2 | Journal of Neuroinflammation

Figure 2

From: Human marrow stromal cells reduce microglial activation to protect motor neurons in a transgenic mouse model of amyotrophic lateral sclerosis

Figure 2

Attenuation of neuronal loss by intrathecal administration of human marrow stromal cells. Cresyl violet staining of the lumbar spinal cord sections from 15-week-old wild-type mice (A) and Cu/Zn superoxide dismutase 1 (SOD1) transgenic mice treated with PBS (B) and human marrow stromal cells (hMSCs) (C) at 200× magnification. (D) Quantitative cell counts of motor neurons in the anterior horn sections. Intrathecally injected hMSCs significantly preserved motor neuron loss in SOD1 transgenic mice at the age of 15 weeks (*P <0.01and **P <0.05 versus PBS alone).

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094