Figure 3

Both ICE KO and WT mice displayed depression-like behaviors following IP LPS challenge. LPS given systemically increased (a) immobility in the FST 24 h after treatment and decreased (b) sucrose preference when measured 24 to 48 h post-treatment similarly in both mouse strains. Data represent averages ± SEM; main effects of LPS where indicated; n = 6 mice per group.