Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response

Table 3 Cross-correlation matrix (Spearman rank correlation coefficients) generated by comparing gene expression levels with clinical parameters of the Rasmussen encephalitis cohort

	CCL5	CCL22	CCL23	CXCL9	CXCL10	FasL	FLAIR	IFN-γ	T2	Time	AED
CCL5	1.00	0.66 ^a	0.31	0.73	0.64	0.83	0.12	0.94	0.17	−0.62	0.07
CCL22		1.00	0.06	0.54	0.54	0.22	−0.44	0.5	−0.08	−0.54	0.28
CCL23			1.00	0.12	−0.08	0.50	0.44	0.28	0.64	−0.21	0.08
CXCL9				1.00	0.92	0.63	0.01	0.82	−0.24	−0.82	−0.07
CXCL10					1.00	0.53	0.00	0.73	−0.33	−0.69	0.00
FasL						1.00	0.60	0.87	0.25	−0.54	−0.02
FLAIR							1.00	0.19	0.31	−0.09	−0.19
IFN-γ								1.00	0.07	−0.64	−0.09
T2									1.00	0.27	0.18
Time ^b										1.00	0.12
AED											1.00

^aStatistically significant correlations are in bold type (P < 0.05). ^bTime from seizure onset to surgery.
AED, antiepileptic drugs.

ISSN: 1742-2094