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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Absence of IL-1β positively affects neurological outcome, lesion development and axonal plasticity after spinal cord injury

Figure 4

Absence of IL-1β in IL-1βKO mice promotes functional outcome after spinal cord injury. (A) Locomotion analysis using the Basso Mouse Scale (BMS) showed a significant increase of neurological outcome after spinal cord compression injury (SCI) in IL-1βKO mice, as evidenced by a difference of1 point of the BMS between treatment groups (6.8 for wildtype (WT) mice and 7.8 for IL-1βKO mice). (B) The paw positioning subscore was significantly different between the two groups. Conversely, the stepping subscore was almost identical. *P <0.05, two-way analysis of variance.

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