Protection of neurological function after MCAO by EA treatment in wild-type but not in MCPIP1 knockout mice. Neurological function assessment was performed 24 h after MCAO. The neurological scores of EA-pretreated wild-type mice were significantly improved compared to that of control. In MCPIP1-deficient mice, there was no significant difference in neurological deficits between the EA-pretreated and the control group. EA, electroacupuncture; MCAO, middle cerebral artery occlusion; MCPIP1, monocyte chemotactic protein-induced protein 1.