Figure 6

Central nervous system (CNS) Ki-67 nuclear proliferation antigen counterstained with hematoxylin. (A) Proliferating cells in the CNS of naive and immunized neonatal (top panels) and adult mice (bottom panels) are indicated by red circles (magnification ×20). (B) Analysis of naive and immunized neonatal and adult CNS by confocal microscopy. Circles indicate GFP⁺ cells. The results shown are examples of two individual mice (M1 and M2) per treatment group (magnification ×63). There was no significant change in the numbers of GFP⁺ cells between naive and immunized mice in either age group.