Figure 6

Plasma anti-oxidant status. The plasma total anti-oxidant status (A) and activity of glutathione reductase (D) were measured with commercially available colorimetric kits in mice maintained on low-fat control chow (LF), diet enriched in saturated fat (SFA), or each diet supplemented with nutraceutical garlic extract-aged (+GEA), alpha-lipoic acid (+ALA), niacin (+Niacin), or nicotinamide (+NA) for nine months. One-way ANOVA followed by Tukey’s post hoc test was used to analyze the statistical significance at P <0.05. (a) Significant difference between LF and SFA; (c) Significant difference between SFA and each nutraceutical treatment. (B and E) show the correlation between parenchymal IgG extravasation and total anti-oxidative status or glutathione reductase activity in all groups. The correlation coefficient was analyzed by Pearson’s analysis. Similarly, (C and F) show Pearson’s correlation coefficient between parenchymal apoB extravasation and total anti-oxidative status or glutathione reductase activity in all groups.