Cytokines and chemokines produced in brains of BALB/c, CcS-11 and STS mice inoculated i.c. with 10 pfu of TBEV. The levels of cytokine/chemokine mRNA [IFNγ (A); TNFα (B); MCP-1 (C); MIP-1β (D); RANTES (E); IL-1α (F); IL-1β (G); IL-2 (H); IL-5 (I); IL-6 (J); and IP-10 (K)] were quantified by real-time RT-PCR and standardized to the mRNA levels of the housekeeping gene, beta actin. Data are expressed as the mean + standard deviation of the fold increase in the level of the mRNA in comparison to uninfected control mice. *p < 0.05; **p < 0.005, ***p < 0.0005 (n = 3 mice per group and experiment).