Table 6 Allele and genotype distributions of the SNPs in male spastic cerebral palsy patients and controls
From: The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral palsy
| Â | Group | Allele frequency | P value | Genotype frequency | P value | Hardy-Weinberg equilibrium | |||
|---|---|---|---|---|---|---|---|---|---|
rs1800796 | Â | C | G | Â | C/C | C/G | G/G | Â | Â |
Spastic | 458 (0.709) | 188 (0.291) | 0.022 | 169 (0.523) | 120 (0.372) | 34 (0.105) | 0.027 | 0.073 | |
Non-spastic | 220 (0.655) | 116 (0.345) | 0.995 | 73 (0.435) | 74 (0.440) | 21 (0.125) | 0.944 | 0.739 | |
| Â | Control | 631 (0.655) | 333 (0.345) | Â | 206 (0.427) | 219 (0.454) | 57 (0.118) | Â | 0.917 |
rs2069837 | Â | A | G | Â | A/A | A/G | G/G | Â | Â |
Spastic | 524 (0.816) | 118 (0.184) | 0.007 a | 220 (0.685) | 84 (0.262) | 17 (0.053) | 0.024 | 0.022 | |
Non-spastic | 266 (0.792) | 70 (0.208) | 0.223 | 106 (0.631) | 54 (0.321) | 8 (0.048) | 0.457 | 0.740 | |
| Â | Control | 718 (0.759) | 228 (0.241) | Â | 279 (0.590) | 160 (0.338) | 34 (0.072) | Â | 0.101 |
rs2066992 | Â | G | T | Â | G/G | G/T | T/T | Â | Â |
Spastic | 189 (0.293) | 455 (0.707) | 0.040 | 34 (0.106) | 121 (0.376) | 167 (0.519) | 0.041 | 0.092 | |
Non-spastic | 114 (0.339) | 222 (0.661) | 0.919 | 19 (0.113) | 76 (0.452) | 73 (0.435) | 0.994 | 0.907 | |
| Â | Control | 330 (0.342) | 634 (0.658) | Â | 55 (0.114) | 220 (0.456) | 207 (0.429) | Â | 0.764 |
rs2069840 | Â | C | G | Â | C/C | C/G | G/G | Â | Â |
Spastic | 599 (0.924) | 49 (0.076) | 0.245 | 276 (0.852) | 47 (0.145) | 1 (0.003) | 0.489 | 0.498 | |
Non-spastic | 302 (0.893) | 36 (0.107) | 0.440 | 135 (0.799) | 32 (0.189) | 2 (0.012) | 0.496 | 0.947 | |
| Â | Control | 877 (0.908) | 89 (0.092) | Â | 396 (0.820) | 85 (0.176) | 2 (0.004) | Â | 0.253 |
rs10242595 | Â | A | G | Â | A/A | A/G | G/G | Â | Â |
Spastic | 575 (0.901) | 63 (0.099) | 0.192 | 261 (0.818) | 53 (0.166) | 5 (0.016) | 0.444 | 0.235 | |
Non-spastic | 295 (0.883) | 39 (0.117) | 0.885 | 130 (0.778) | 35 (0.210) | 2 (0.012) | 0.729 | 0.835 | |
| Â | Control | 838 (0.880) | 114 (0.120) | Â | 372 (0.782) | 94 (0.197) | 10 (0.021) | Â | 0.168 |