Figure 12

Pericytes respond to inflammatory cues by nuclear translocation of NFκB. Immunocytochemistry of NFκB p65 staining in primary human brain pericytes treated for two hours with vehicle (0.1% BSA in PBS), IFNγ (10 ng/ml), TNFα (50 ng/ml), IL-1β (10 ng/ml), or LPS (10 ng/ml). (NFκB p65 (green), Hoechst (blue)). Scale bar = 100 μm. Images are from one representative experiment that has been repeated in three separate cases. LPS, lipopolysaccharide; NFκB, nuclear factor light chain enhancer of activated B cells.