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Table 2 Working range and proportion below the minimal detection level (MDL) for each analyte measured in newborn dried blood by case-control status - the Early Markers for Autism study

From: Neonatal cytokines and chemokines and risk of Autism Spectrum Disorder: the Early Markers for Autism (EMA) study: a case-control study

Analytes

Working range (pg/ml)

ASD Cases (n =84)

GP (n =159)

DD (n = 49)

  

% below MDL

% below MDL

% below MDL

MCP-1

13.03 – 9,160

19.0

18.0

26.3

MIP-1α

6.1 – 28,800

0.0

1.2

4.1

RANTES

22.36 – 19,100

0.0

0.6

2.0

Eotaxin

1.37 – 9,200

19.0

9.0

14.3

IFN-γ

0.58 – 11,370

77.4

73.0

86.0

IL-1β

2.5 – 5,470

77.4

76.8

79.6

IL-2

1.45 – 9,530

67.9

69.2

83.7

IL-4

2.21 – 14,470

77.4

74.2

86.0

IL-6

1.88 – 12,360

77.4

74.8

79.6

IL-10

3.4 – 22,350

53.6

54.1

51.0

IL-5

1.75 – 11,490

100

100

100

IL-8

6.23 – 13,630

97.6

98.7

98.0

IL-12p40

2.74 – 6,000

100

99.4

100

TNF-α

3.96 – 8,660

100

99.4

100

IP-10

2.01 – 1,420

100

100

100

MIP-1β

5.3 – 10,370

96.4

94.3

98.0

GM-CSF

0.88 – 5,760

98.8

99.4

97.9

  1. ASD: Autism Spectrum Disorder; DD: developmental delay; GP: general population; MDL: minimal detection level.