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Table 2 Working range and proportion below the minimal detection level (MDL) for each analyte measured in newborn dried blood by case-control status - the Early Markers for Autism study

From: Neonatal cytokines and chemokines and risk of Autism Spectrum Disorder: the Early Markers for Autism (EMA) study: a case-control study

Analytes Working range (pg/ml) ASD Cases (n =84) GP (n =159) DD (n = 49)
   % below MDL % below MDL % below MDL
MCP-1 13.03 – 9,160 19.0 18.0 26.3
MIP-1α 6.1 – 28,800 0.0 1.2 4.1
RANTES 22.36 – 19,100 0.0 0.6 2.0
Eotaxin 1.37 – 9,200 19.0 9.0 14.3
IFN-γ 0.58 – 11,370 77.4 73.0 86.0
IL-1β 2.5 – 5,470 77.4 76.8 79.6
IL-2 1.45 – 9,530 67.9 69.2 83.7
IL-4 2.21 – 14,470 77.4 74.2 86.0
IL-6 1.88 – 12,360 77.4 74.8 79.6
IL-10 3.4 – 22,350 53.6 54.1 51.0
IL-5 1.75 – 11,490 100 100 100
IL-8 6.23 – 13,630 97.6 98.7 98.0
IL-12p40 2.74 – 6,000 100 99.4 100
TNF-α 3.96 – 8,660 100 99.4 100
IP-10 2.01 – 1,420 100 100 100
MIP-1β 5.3 – 10,370 96.4 94.3 98.0
GM-CSF 0.88 – 5,760 98.8 99.4 97.9
  1. ASD: Autism Spectrum Disorder; DD: developmental delay; GP: general population; MDL: minimal detection level.