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Figure 5 | Journal of Neuroinflammation

Figure 5

From: NitroDIGE analysis reveals inhibition of protein S-nitrosylation by epigallocatechin gallates in lipopolysaccharide-stimulated microglial cells

Figure 5

Functional annotation and pathway analysis. (A) Three subsets of SNO-proteins with overlaps in between were identified from different treatments in this study. There are three common proteins shared by the three data sets, including TCP1, ISYNA1, and PRDX2. (B) Cellular location of the 78 SNO-proteins responding to EGCG treatment in LPS-stimulated BV-2 cells. (C) The top protein interaction network associated with EGCG-treatment in LPS-stimulated BV-2 cells was predicted by IPA and presented. Twenty-four SNO-proteins are involved in this network. The intensity of green color indicates the level of down-regulation. (D) Top 10 IPA canonical pathways targeted by EGCG in LPS-stimulated BV-2 cells.

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Journal of Neuroinflammation

ISSN: 1742-2094