Figure 1
TLR expression in the mouse trigeminal ganglia. Mice were either infected intranasally with 106 p.f.u. of HSV-1 or were not infected, and they were euthanized 5 days thereafter. The trigeminal ganglia were collected, and the RNA was extracted, reverse transcribed in cDNA and real-time PCR for TLR expression indices for C57BL/6 or the indicated knockout (NI) (n = 4) or the respective infected groups (n = 6 to 9) were obtained (*P <0.05; **P <0.01; ***P <0.001 when comparing the infected animals with the respective non-infected animals); (#P <0.05, ##P <0.01, ###P <0.001, when comparing the infected C57BL/6 mice with the infected knockout mice). The results are representative of two experiments that yielded similar results.