Skip to main content

Table 1 Affinity binding and rate constants of Ilantide, interleukin 1β and interleukin 1 receptor antagonist to interleukin 1 receptor type I a

From: Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist

Ligands ka(M-1s-1) kd(s-1) Kd(M)
Ilantide 1.84 ± 0.20 × 105 2.69 ± 0.58 × 10-3 2.75 × 10-8 ± 7 .86 × 10-9
IL-1Ra 1.47 ± 5.53 × 105 3.62 ± 0.65 × 10-3 4.80 × 10-8 ± 1.32 × 10-8
IL-1β 8.56 ± 2.79 × 105 7.53 ± 2.03 × 10-4 1.71 × 10-7 ± 7.07 × 10-9
  1. aIL-1β, interleukin 1β; IL-1Ra, interleukin 1 receptor antagonist.