Table 1 Affinity binding and rate constants of Ilantide, interleukin 1β and interleukin 1 receptor antagonist to interleukin 1 receptor type I a
From: Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist
Ligands | ka(M-1s-1) | kd(s-1) | Kd(M) |
|---|---|---|---|
Ilantide | 1.84 ± 0.20 × 105 | 2.69 ± 0.58 × 10-3 | 2.75 × 10-8 ± 7 .86 × 10-9 |
IL-1Ra | 1.47 ± 5.53 × 105 | 3.62 ± 0.65 × 10-3 | 4.80 × 10-8 ± 1.32 × 10-8 |
IL-1β | 8.56 ± 2.79 × 105 | 7.53 ± 2.03 × 10-4 | 1.71 × 10-7 ± 7.07 × 10-9 |