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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Knockout of CXCR5 increases the population of immature neural cells and decreases proliferation in the hippocampal dentate gyrus

Figure 1

Effect of CXCR5 deficieny on neurogenesis in the adult dentate gyrus. (A) In CXCR5-/- animals the number of Ki67 positive cells was significantly reduced compared to WT controls (P = 0.009; n = 6 per group). (B) In CXCR5-/- animals the number of DCX positive cells was significantly increased compared to WT controls (P = 0.02; n = 6 per group). (C) In CXCR5-/- animals the number of Nestin positive cells was significantly increased compared to WT controls (P = 0.0008; n = 6 per group). Representative images of Ki67 (C, D), DCX (E, F) and Nestin (H, I) staining.

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