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Figure 9 | Journal of Neuroinflammation

Figure 9

From: Antibacterial responses of retinal Müller glia: production of antimicrobial peptides, oxidative burst and phagocytosis

Figure 9

The mechanisms of the Müller glial antimicrobial response. Following microbial (bacteria) insult, Müller glia elicit innate defense responses in an attempt to limit bacterial growth. These include the production of antimicrobial peptides (AMPs), reactive oxygen species (ROS), and reactive nitrogen species (RNS), which possess the ability to kill the bacteria directly. Additionally, Müller glia can phagocytize and kill the pathogens intracellularly.

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Journal of Neuroinflammation

ISSN: 1742-2094