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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Extensive dysregulations of oligodendrocytic and astrocytic connexins are associated with disease progression in an amyotrophic lateral sclerosis mouse model

Figure 4

Quantitative immunoblot analysis of Cxs in mSOD1-Tg and non-Tg mice at 18 weeks of age. (A) Representative images of GFAP, EAAT2, Cx43, Cx30, Cx47, Cx32, and MOG immunoblots obtained from mSOD1-Tg mice and non-Tg mice (n = 3 per group). GAPDH blots for loading controls are shown under each protein blot. (B) Results of quantitative analysis for each protein as indicated. Expression levels of EAAT2 and Cx32 are significantly decreased in mSOD1-Tg mice compared with non-Tg mice. By contrast, the level of GFAP expression is increased in mSOD1-Tg mice than non-Tg mice. The expression levels of the other markers, including Cx43, Cx30, and Cx47, are not significantly different between the two groups.

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Journal of Neuroinflammation

ISSN: 1742-2094