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Figure 8 | Journal of Neuroinflammation

Figure 8

From: Extensive dysregulations of oligodendrocytic and astrocytic connexins are associated with disease progression in an amyotrophic lateral sclerosis mouse model

Figure 8

Cleaved caspase-3 expression in the anterior horn oligodendrocytes of mSOD1-Tg mice. Double immunostaining for cleaved caspase-3 and CC1 was performed in the anterior horns of spinal cords from non-Tg and mSOD1-Tg mice at 20 weeks of age. (A- C) Immunoreactivity for cleaved caspase-3 is never observed in the anterior horn of non-Tg mice. (D-F) Cleaved caspase-3 expression is detected in a small number of CC1-positive mature oligodendrocytes in the anterior horns of mSOD1-Tg mice (arrows). Scale bar; 20 μm (A-F).

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Journal of Neuroinflammation

ISSN: 1742-2094