Figure 6From: Epidermal growth factor receptor inhibitor ameliorates excessive astrogliosis and improves the regeneration microenvironment and functional recovery in adult rats following spinal cord injury PD168393 reduced demyelination after spinal cord injury (SCI). A 15 mm length of spinal cord centered at the injury site was harvested at day 28 post-injury and serially sectioned (n = 5/group). Representative transverse Luxol Fast Blue stained sections at the epicenter and in 1 mm increments rostral and caudal to the epicenter. Epicenter sections are indicated by arrows. Scale bar = 1 mm (A). Graphical representation shows statistically significant reduction in lesion cavity volume following PD168393 treatment as well as considerable decrease in myelin loss (B) (n = 5, *P < 0.05 compared to control).Back to article page