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Table 3 Significance of differentially expressed target genes following chronic inflammatory models

From: Peripheral inflammation is associated with remote global gene expression changes in the brain

Gene Significance of fold change in treatment group compared to vehicle control group (↑, upregulated; ↓, downregulated)
  IMQ (P) TPA (P)
  Brain PBLs Brain PBLs
Ctsc ↑ 0.0187 Not significant ↓ 0.0026 Not significant
Cxcl10 ↑ 0.0156 Not significant Not significant Not significant
Gbp2 ↑ 0.0177 Not significant ↓ 0.0401 Not significant
Gbp3 ↑ 0.0032 Not significant Not significant Not significant
Gbp4 ↑ 0.0254 Not significant Not significant ↓ 0.0490
Ifit1 ↑ 0.0053 Not significant Not significant Not significant
Ifitm3 ↑ 0.0010 Not significant Not significant Not significant
Igrm1 ↑ 0.0005 Not significant Not significant Not significant
Irf7 ↑ 0.0029 Not significant Not significant Not significant
Lgals3bp ↑ 0.0003 Not significant Not significant Not significant
Oasl2 ↑ 0.0015 Not significant Not significant Not significant
Rtp4 ↑ 0.0002 Not significant Not significant Not significant
Sp100 ↑ 0.0087 Not significant Not significant Not significant
Stat1 ↑ 0.0043 Not significant ↓ 0.0241 Not significant
  1. Significance of differential gene expression was calculated separately for individual genes in each tissue using an unpaired t test.