Table 3 Significance of differentially expressed target genes following chronic inflammatory models
From: Peripheral inflammation is associated with remote global gene expression changes in the brain
Gene | Significance of fold change in treatment group compared to vehicle control group (↑, upregulated; ↓, downregulated) | |||
|---|---|---|---|---|
| Â | IMQ (P) | TPA (P) | ||
| Â | Brain | PBLs | Brain | PBLs |
Ctsc | ↑ 0.0187 | Not significant | ↓ 0.0026 | Not significant |
Cxcl10 | ↑ 0.0156 | Not significant | Not significant | Not significant |
Gbp2 | ↑ 0.0177 | Not significant | ↓ 0.0401 | Not significant |
Gbp3 | ↑ 0.0032 | Not significant | Not significant | Not significant |
Gbp4 | ↑ 0.0254 | Not significant | Not significant | ↓ 0.0490 |
Ifit1 | ↑ 0.0053 | Not significant | Not significant | Not significant |
Ifitm3 | ↑ 0.0010 | Not significant | Not significant | Not significant |
Igrm1 | ↑ 0.0005 | Not significant | Not significant | Not significant |
Irf7 | ↑ 0.0029 | Not significant | Not significant | Not significant |
Lgals3bp | ↑ 0.0003 | Not significant | Not significant | Not significant |
Oasl2 | ↑ 0.0015 | Not significant | Not significant | Not significant |
Rtp4 | ↑ 0.0002 | Not significant | Not significant | Not significant |
Sp100 | ↑ 0.0087 | Not significant | Not significant | Not significant |
Stat1 | ↑ 0.0043 | Not significant | ↓ 0.0241 | Not significant |