Figure 2

Effect of the diabetic condition on inflammatory gene expression in the peritoneal cells before and after stroke. (A) Flow cytometry analysis of peritoneal immune cells. The cells in the gated area indicate CD11b⁺/Lin^- (CD11b^high/Lin^low) monocytes/macrophages. (B to E) Gene expression of MCP-1 (B), IL-6 (C), CCR2 (D), and CD36 (E) in normal and diabetic peritoneal cells prior to ischemia (pre-) and at 6 h (6 h-post) and 72 h after stroke (72 h-post), n = 9 to 13/group. ND, normal mice; DD, diabetic mice; Lin, markers for lymphocytes/NK cells/granulocytes; CD11b, a marker for mononuclear phagocytes; ^* P <0.05, ^** P <0.01 vs. ND.