Figure 1
From: Roles of NFκB-miR-29s-MMP-2 circuitry in experimental choroidal neovascularization
Increased MMP-2 staining in the choroidal-RPE membrane of CNV model. Cryosections from non-treated (left panel) and laser-lesion (right panel) eyeballs between 12and 15 days after photocoagulation were processed for CD31 (top row, dark arrow) and MMP-2 staining (bottom row, white arrow) as described in Methods. *marks the margin of the retinal pigment epithelial cell layer (top row). The images (from control or CNV) are typical of those in triplicate experiments and the images for each experiment were selected from those processed with three eyeballs.Ch, choroid; Ret, retina; CNV, choroidal neovascularization; RPE, retinal pigment epithelia; MMP-2, Matrix metallopeptidase-2. Scale bar = 50 μ.