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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Impact of the neutrophil response to granulocyte colony-stimulating factor on the risk of hemorrhage when used in combination with tissue plasminogen activator during the acute phase of experimental stroke

Figure 1

Effect of subcutaneous administration of G-CSF (60 μg/kg; 30 μL) or vehicle (NaCl 0.9% , 30 μL) on the risk of hemorrhages. (a) Number of hemorrhages in the infarct area (mean ± SD). (b) Hemorrhages were seen in vivo on T2-weighted MRI images. (c) Macroscopically visible on histological sections as petechiae or hematoma in the infarct area . Rats were all submitted to ischemia/reperfusion, tPA treatment and 72 hours of reperfusion. Scale bar = 500 μm. *P <0.05. G-CSF, granulocyte colony stimulating factor; MRI, magnetic resonance imaging; tPA, tissue plasminogen activator, SD standard deviation.

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Journal of Neuroinflammation

ISSN: 1742-2094