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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Infiltrative microgliosis: activation and long-distance migration of subependymal microglia following periventricular insults

Figure 4

Dynamics of infiltrative microgliosis. (A) 2D projections of confocal images demonstrate three migratory cells (large and small white arrows) migrating into the cSO. white arrowhead, non-migratory cell for reference. e, ependyma; cSO, stratum oriens. See also Video 2. (B) Migration was highly directed from ventricle to hippocampus, five representative cells from a single experiment. lv, lateral ventricle; black stars, cell origin (C) Highly polarized, migratory morphologies of RHO+ cells as demonstrated by confocal 3D reconstruction. cb, cell body; lpr, leading process; tpr, trailing process.

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