Table 2 Cerebral and plasma Aβ levels in J20 APP-tg mice
TBS soluble* | Guanidine soluble* | Plasma^ | |||
|---|---|---|---|---|---|
Treatment group† | Aβx-40 | Aβx-42 | Aβx-40 | Aβx-42 | Aβ1-total |
LT(R192G) | 8.1 ± 1.8 | 12.3 ± 1.1 | 485.8 ± 123.0 | 2017.5 ± 659.1 | 370 ± 29 |
Aβ40/42 | 6.0 ± 1.8 | 10.1 ± 3.0 | 178.1 ± 49.8 | 757.6 ± 186.7 | 522 ± 81 |
Aβ1–15 | 9.4 ± 1.6 | 13.3 ± 1.9 | 331.7 ± 71.2 | 2024 ± 829.9 | 316 ± 46 |
dAβ1–15 | 5.8 ± 1.9 | 7.8 ± 2.5 | 224.1 ± 58.9 | 1345 ± 551.5 | 344 ± 86 |