Figure 1
From: Simvastatin inhibits interferon-γ-induced MHC class II up-regulation in cultured astrocytes
A. Percentage of MHC class II positive astrocytes (mean ± SEM). a, non-stimulated conditions; b, after IFN-γ stimulation, c, IFN-γ + 10-11 M simvastatin; d, IFN-γ + 10-10 M simvastatin; e, IFN-γ + 10-9 M simvastatin; f, IFN-γ + 10-8 M simvastatin; g, IFN-γ + 10-8 M simvastatin + 100 μM mevalonate. B. Immunofluorescence staining for MHC class II. a, non-stimulated conditions; b, after IFN-γ stimulation, c, IFN-γ + 10-8 M simvastatin; d, IFN-γ + 10-8 M simvastatin + 100 μM mevalonate.