Figure 1From: Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Aβ immunotherapyAβ levels in APP/IL-1 R1-/- mice, APP/IL-1 R1+/-littermates and wild type Tg2576 mice at 6 months, 9 months and 15 months of age. Groups of mice were killed at the indicated time points and both SDS-soluble (SDS) and SDS-insoluble, formic acid extractable (FA) fractions of Aβ40 and Aβ42 were measured by capture ELISA.Back to article page