C9 staining in substantia nigra specimens. Fig. 2A: Staining of multiple Lewy bodies within a melanized neuron in a PD specimen; adjacent melanized neuron (arrow) and its axon are also C9-positive; Fig. 2B: immunoreactivity for C9 in a Lewy body (arrowhead) and in melanin-depleted neurons (arrows) in a different PD specimen; Fig. 2C: staining of melanized neuron (arrow) and its processes in a DLB specimen; Fig 2D: multiple immunoreactive melanized neurons in an aged normal specimen. (Fig. 2A, bar = 10 μm; Figs. 2B–D, bar = 50 μm; immunoreactive structures are dark blue or gray, in contrast to brown melanin and yellow background).