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Table 3 Physiological parameters.

From: Parecoxib is neuroprotective in spontaneously hypertensive rats after transient middle cerebral artery occlusion: a divided treatment response?

Group SHR tMCAo, parecoxib (n = 21) SHR tMCAo, saline (n = 21) SHR sham, parecoxib (n = 8) SHR sham, saline (n = 9)
MABP, before (mmHg) 137.0 ± 18.82 139.2 ± 17.87 152.3 ± 12.14 144.8 ± 12.02
MABP, during (mmHg) 129.3 ± 19.64 131.4 ± 20.39 141.5 ± 12.37 132.6 ± 16.49
MABP, after (mmHg) 111.4 ± 20.36 120.9 ± 24.33 136.8 ± 19.62 135.0 ± 28.29
HR, before (BPM) 374 ± 28.6 364 ± 29.2 363 ± 25.3 373 ± 25.9
HR, during (BPM) 372 ± 24.5 379 ± 28.5 359 ± 24.8 368 ± 21.0
HR, after (BPM) 336 ± 28.3 353 ± 25.3 335 ± 25.8 349 ± 27.3
Rectal Temp., before (°C) 37.8 ± 0.40 37.6 ± 0.38 37.6 ± 0.22 37.4 ± 0.30
Rectal Temp., during (°C) 37.8 ± 0.15 37.7 ± 0.14 37.7 ± 0.07 37.7 ± 0.11
Rectal Temp., after (°C) 37.5 ± 0.27 37.6 ± 0.24 37.3 ± 0.18 37.4 ± 0.25
pH, before 7.46 ± 0.04 7.45 ± 0.03 7.46 ± 0.02 7.44 ± 0.02
pH, during 7.44 ± 0.02 7.44 ± 0.02 7.45 ± 0.01 7.45 ± 0.02
pH, after 7.43 ± 0.02 7.42 ± 0.02 7.44 ± 0.02 7.44 ± 0.03
pCO2, before (kPa) 5.70 ± 0.65 5.71 ± 0.58 5.81 ± 0.42 5.92 ± 0.28
pCO2, during (kPa) 5.53 ± 0.33 5.52 ± 0.35 5.37 ± 0.22 5.21 ± 0.17
pCO2, after (kPa) 5.55 ± 0.21 5.47 ± 0.43 5.20 ± 0.33 5.12 ± 0.22*
pO2, before (kPa) 28.36 ± 5.01 29.13 ± 3.68 29.17 ± 2.65 29.87 ± 1.65
pO2, during (kPa) 29.10 ± 4.24 27.76 ± 4.36 28.49 ± 3.11 27.42 ± 4.17
pO2, after (kPa) 29.27 ± 3.47 29.20 ± 2.92 28.75 ± 2.80 28.53 ± 3.29
Hemoglobin, before (mmol/L) 9.5 ± 0.42 9.5 ± 0.41 9.5 ± 0.46 9.7 ± 0.77
Hemoglobin, during (mmol/L) 8.6 ± 0.45 8.7 ± 0.41 8.9 ± 0.47 8.8 ± 0.50
Hemoglobin, after (mmol/L) 8.1 ± 0.47 8.1 ± 0.51 8.3 ± 0.39 8.2 ± 0.56
Glucose, before (mmol/L) 12.7 ± 2.72 13.0 ± 2.98 15.8 ± 1.45* 15.8 ± 0.77*
Glucose, during (mmol/L) 10.0 ± 2.74 10.3 ± 2.68 13.1 ± 0.78* 12.0 ± 1.62
Glucose, after (mmol/L) 9.8 ± 2.70 10.3 ± 2.88 13.1 ± 2.28* 11.9 ± 1.44
Body weight (grams) 314.9 ± 16.74 309.1 ± 20.74 300.5 ± 16.82 294.1 ± 22.39
Duration of anesthesia (min) 154.2 ± 6.94 156.9 ± 17.72 154.8 ± 7.48 156.2 ± 9.01
  1. Physiological parameters monitored before, during and after tMCAo or sham procedure in all four groups. Mean values ± SD. One-way ANOVA with Bonferroni post hoc analysis was used for the comparison between the groups. * indicate p < 0.05.