Table 3 Physiological parameters.
Group | SHR tMCAo, parecoxib (n = 21) | SHR tMCAo, saline (n = 21) | SHR sham, parecoxib (n = 8) | SHR sham, saline (n = 9) |
|---|---|---|---|---|
MABP, before (mmHg) | 137.0 ± 18.82 | 139.2 ± 17.87 | 152.3 ± 12.14 | 144.8 ± 12.02 |
MABP, during (mmHg) | 129.3 ± 19.64 | 131.4 ± 20.39 | 141.5 ± 12.37 | 132.6 ± 16.49 |
MABP, after (mmHg) | 111.4 ± 20.36 | 120.9 ± 24.33 | 136.8 ± 19.62 | 135.0 ± 28.29 |
HR, before (BPM) | 374 ± 28.6 | 364 ± 29.2 | 363 ± 25.3 | 373 ± 25.9 |
HR, during (BPM) | 372 ± 24.5 | 379 ± 28.5 | 359 ± 24.8 | 368 ± 21.0 |
HR, after (BPM) | 336 ± 28.3 | 353 ± 25.3 | 335 ± 25.8 | 349 ± 27.3 |
Rectal Temp., before (°C) | 37.8 ± 0.40 | 37.6 ± 0.38 | 37.6 ± 0.22 | 37.4 ± 0.30 |
Rectal Temp., during (°C) | 37.8 ± 0.15 | 37.7 ± 0.14 | 37.7 ± 0.07 | 37.7 ± 0.11 |
Rectal Temp., after (°C) | 37.5 ± 0.27 | 37.6 ± 0.24 | 37.3 ± 0.18 | 37.4 ± 0.25 |
pH, before | 7.46 ± 0.04 | 7.45 ± 0.03 | 7.46 ± 0.02 | 7.44 ± 0.02 |
pH, during | 7.44 ± 0.02 | 7.44 ± 0.02 | 7.45 ± 0.01 | 7.45 ± 0.02 |
pH, after | 7.43 ± 0.02 | 7.42 ± 0.02 | 7.44 ± 0.02 | 7.44 ± 0.03 |
pCO2, before (kPa) | 5.70 ± 0.65 | 5.71 ± 0.58 | 5.81 ± 0.42 | 5.92 ± 0.28 |
pCO2, during (kPa) | 5.53 ± 0.33 | 5.52 ± 0.35 | 5.37 ± 0.22 | 5.21 ± 0.17 |
pCO2, after (kPa) | 5.55 ± 0.21 | 5.47 ± 0.43 | 5.20 ± 0.33 | 5.12 ± 0.22* |
pO2, before (kPa) | 28.36 ± 5.01 | 29.13 ± 3.68 | 29.17 ± 2.65 | 29.87 ± 1.65 |
pO2, during (kPa) | 29.10 ± 4.24 | 27.76 ± 4.36 | 28.49 ± 3.11 | 27.42 ± 4.17 |
pO2, after (kPa) | 29.27 ± 3.47 | 29.20 ± 2.92 | 28.75 ± 2.80 | 28.53 ± 3.29 |
Hemoglobin, before (mmol/L) | 9.5 ± 0.42 | 9.5 ± 0.41 | 9.5 ± 0.46 | 9.7 ± 0.77 |
Hemoglobin, during (mmol/L) | 8.6 ± 0.45 | 8.7 ± 0.41 | 8.9 ± 0.47 | 8.8 ± 0.50 |
Hemoglobin, after (mmol/L) | 8.1 ± 0.47 | 8.1 ± 0.51 | 8.3 ± 0.39 | 8.2 ± 0.56 |
Glucose, before (mmol/L) | 12.7 ± 2.72 | 13.0 ± 2.98 | 15.8 ± 1.45* | 15.8 ± 0.77* |
Glucose, during (mmol/L) | 10.0 ± 2.74 | 10.3 ± 2.68 | 13.1 ± 0.78* | 12.0 ± 1.62 |
Glucose, after (mmol/L) | 9.8 ± 2.70 | 10.3 ± 2.88 | 13.1 ± 2.28* | 11.9 ± 1.44 |
Body weight (grams) | 314.9 ± 16.74 | 309.1 ± 20.74 | 300.5 ± 16.82 | 294.1 ± 22.39 |
Duration of anesthesia (min) | 154.2 ± 6.94 | 156.9 ± 17.72 | 154.8 ± 7.48 | 156.2 ± 9.01 |