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Table 1 Numbers of CCR1, CCR2 and CCR5 mRNA-expressing cells per square unit (1.9 × 104 μm2) in rat EAE lesions (mean ± SEM)

From: Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE

  CCR1 CCR2 CCR5
PPWM 1.7 ± 1.3 1.7 ± 0.8 6.2 ± 1.7
EA 35.3 ± 7.6a 15.6 ± 3.3a 80.5 ± 14.8a
LA 106.4 ± 8.5b 30.2 ± 5.3b 65.1 ± 14.8a
IADM 12.9 ± 4.1c 3.6 ± 1.0 23.6 ± 6.3
  1. a Statistically significant against IADM lesions and PPWM areas
  2. b Statistically significant against EA and IADM lesions and PPWM areas
  3. c Statistically significant against PPWM areas
  4. EA = early active lesions, LA = late active lesions, IADM = inactive completely demyelinated lesions, PPWM = periplaque white matter.