C1q and C3 mRNAs were increased in Tg-SwDI mouse brains. Real-time PCRs for C1q (A) and C3 (B) were performed on cDNAs synthesized from mRNAs extracted from twelve months old C57BL/6 (white bars) and Tg-SwDI (gray bars) mouse cortical and thalamic regions. Data shown are mean ± S.D. (n = 9). Both C1q and C3 were statistically significantly higher in transgenic mice over wild-type (*p < 0.02) except C1q in cortex.