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Figure 9 | Journal of Neuroinflammation

Figure 9

From: Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes

Figure 9

mRNA levels in cortex, 8 months. mRNA levels in WT and TG mice (8 months). mRNA levels are raised in TG/VEH vs. WT/VEH for MIP1-α (A), MIP1-β (B), TNF-α (C), GFAP (D) RANTES (E). There is a significant reduction in MIP1-α mRNA levels in TG/DSP-4 vs. TG/VEH. DSP-4 increased iNOS (F) in WT mice only and iNOS was not raised in TG/VEH or TG/DSP-4 vs. WT/VEH.

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Journal of Neuroinflammation

ISSN: 1742-2094