mRNA levels in cortex, 8 months. mRNA levels in WT and TG mice (8 months). mRNA levels are raised in TG/VEH vs. WT/VEH for MIP1-α (A), MIP1-β (B), TNF-α (C), GFAP (D) RANTES (E). There is a significant reduction in MIP1-α mRNA levels in TG/DSP-4 vs. TG/VEH. DSP-4 increased iNOS (F) in WT mice only and iNOS was not raised in TG/VEH or TG/DSP-4 vs. WT/VEH.