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Table 1 Dosage range of Stx2 and clinical findings

From: Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2

Dose (μg/kg) neurological symptoms (%) Diarrhea/occult blood Body weight loss (%)
0.1 1a /5 (20) -~+/-~+ 8.0~38.8
0.25 0/4 (0) +/+ 13.2~25.6
0.5 0/4 (0) +/+ 22.0~36.7
1.0 2/4 (50) +/+ 26.7
2.0 5/6 (83.3) +/+ -b
4.0 5/6 (83.3) +/+ -b
  1. aTransient gait disturbance was observed on the 4th to 6th day after administration of Stx2.
  2. bnot measured.