Figure 10
From: Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis
SLPI prevents TNFα-induced IκBα degradation and suppresses HES1. A: Western Blot for IκBα with protein extracts from neural stem cells stimulated for the indicated periods with 10 ng/ml TNFα with (+) or without (-) 500 ng/ml SLPI. Presentation of one of two experiments. B: RealTime-PCR assessment of HES1 expression (n = 3, + std dev) in rat adult NSC after an incubation period of three days with the indicated amounts of SLPI and consecutive four days in differentiation medium. Presentation of a representative result of three experiments. *:p < 0.05, **: p < 0.01 (according to a One Way ANOVA analysis of variance (Holm-Sidak method)).