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Table 3 Expression of genes related to antigen presentation within the spinal cord during the disease course of MOG-induced EAE

From: Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis

Probeset

Gene

healthy

stddev

acute

stddev

remission

stddev

relapsing

stdev

H33922_f_at

RT1 class Ib gene

224.7

35.3

1085.7

102.5

382.8

88.0

677.9

350.6

L40362_f_at

 

242.0

33.1

913.6

141.0

463.3

84.2

523.5

250.4

M11094_g_at

 

50.0

9.2

182.4

36.4

117.8

13.4

114.7

32.7

M11071_f_at

 

919.4

157.0

3552.1

547.2

2325.2

649.9

2208.1

612.6

M24026_f_at

 

381.6

52.5

1476.6

78.8

915.2

135.4

1016.0

408.4

M24324_f_at

 

420.3

27.9

1904.7

121.0

1016.5

195.5

1277.4

592.5

M31018_f_at

 

484.4

56.8

2383.8

392.3

1554.6

336.0

1601.8

614.5

M31038_at

 

30.5

4.2

180.4

36.4

54.4

4.3

139.7

110.0

rc_AA858651_f_at

 

386.5

82.9

1585.7

203.2

887.5

152.6

982.4

295.6

rc_AA945159_s_at

 

115.0

69.6

502.1

439.7

667.2

69.0

304.2

271.3

rc_AI103500_f_at

 

290.1

9.2

2175.2

48.2

513.8

100.9

1069.4

780.4

rc_AI176358_f_at

 

299.3

20.7

1176.6

270.5

611.3

42.9

733.8

256.9

rc_AI235223_at

 

213.6

41.4

947.6

95.3

844.3

112.6

714.9

227.9

AF025308_f_at

MHC class Ib antigen (RT1.Cl)

127.5

11.9

696.2

190.0

161.7

19.6

413.8

335.9

L40364_f_at

MHC class I RT1.O type 149 processed pseudogene

438.8

41.1

1100.0

178.2

577.9

87.3

722.8

470.2

AF029240_at

MHC class Ib RT1.S3

21.8

8.6

94.2

23.8

55.2

4.2

35.6

13.9

AF029240_g_at

 

99.5

9.0

267.9

94.7

185.6

48.2

135.9

50.5

rc_AI235890_s_at

 

34.1

15.5

228.3

13.5

55.6

21.5

63.6

42.4

AF074608mRNA_f_at

MHC class I antigen (RT1.EC2)

186.2

21.9

612.1

93.6

493.7

119.8

496.0

116.0

M64795_f_at

MHC class I antigen gene (RT1-u haplotype)

42.1

6.0

322.6

37.7

59.5

13.0

179.8

148.6

rc_AI235223_at

RT1 class I, A3

213.6

41.4

947.6

95.3

844.3

112.6

714.9

227.9

X57523_at

Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

78.1

11.6

292.0

108.8

88.2

24.2

123.5

44.1

X57523_g_at

 

21.9

2.9

308.5

105.5

86.4

31.8

66.2

30.7

X63854_at

Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

44.8

9.5

125.4

26.0

60.6

1.1

74.5

23.5

rc_AI170268_at

Beta-2-microglobulin

738.0

270.5

2559.2

864.8

4295.5

654.1

2487.2

1142.1

K02815_s_at

Butyrophilin-like 2 (MHC class II associated)

86.3

2.8

869.9

155.5

485.3

199.1

519.6

306.1

M15562_at

MHC class II RT1.u-D-alpha chain mRNA, 3' end

77.3

5.9

1441.2

355.7

1088.1

375.5

765.1

244.6

M15562_g_at

 

205.6

126.3

4436.1

1998.8

5944.8

1630.7

3230.7

1453.0

Z49761_at

Major histocompatibility complex, class II, DM alpha

21.5

10.3

343.5

52.4

96.9

5.7

125.4

66.4

U31598_s_at

 

95.9

29.7

799.4

114.3

108.6

12.0

266.3

169.8

U31599_at

Major histocompatibility complex, class II, DM beta

4.5

1.9

256.8

107.7

22.7

6.6

68.0

63.0

U31599_g_at

 

9.9

2.5

441.4

69.5

69.1

9.8

156.8

116.4

rc_AI171966_at

 

42.7

8.0

1233.0

256.7

433.0

94.2

428.3

286.4

X13044_at

CD74 antigen (invariant polpypeptide of major histocompatibility class II antigen-associated)

89.2

22.8

2866.0

381.1

2330.7

638.0

1867.9

218.7

X13044_g_at

 

86.5

22.6

3206.0

873.7

3432.7

796.6

2228.7

364.2

X14254cds_g_at

 

73.3

18.6

1947.4

288.9

1298.5

384.1

1417.0

427.4

X53054_at

MHC class II DLA DRB1 beta chain

1.9

0.3

181.8

49.4

99.7

30.8

101.5

28.4

X53054_g_at

 

40.3

7.2

788.7

134.2

745.6

233.2

556.7

157.9

rc_AI045321_at

Class II, major histocompatibility complex, transactivator

41.0

11.6

245.2

38.0

124.3

30.3

61.7

21.0

rc_AI228153_s_at

MHC class II antigen RT1.B-1 beta-chain

25.3

5.9

963.5

320.2

720.3

126.6

451.0

228.3

X56596_at

 

51.0

18.3

1064.2

72.4

400.0

84.6

439.8

208.1

M36151cds_s_at

 

39.1

6.0

1090.4

348.8

250.9

68.0

554.4

471.8