Figure 6
From: P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis
Microglial activation is similar in P2x7 and WT brain. Serial sections from WT (A, B, C) and P2x7 null (E, F, G) mice as described in Figure 5 were stained with monoclonal antibody F4/80 to detect activated microglia and macrophages. Representative images from one mouse in each group show the presence of cells with characteristic morphology of microglia in cerebellar white matter ('WM', panels A, D) and corpus callosum ('CC', panels C, F); and diffuse staining in cerebellar granule layer ('GL', panels B, E).