Post-injury treatment with DEDA protects the brain against IR injury and improves neurologic score. (A) Photographs showing the effect of DEDA (1 mg/kg) administered at reperfusion and repeated at 3 h following reperfusion after 60 min MCAO on TTC-stained sections, (B) Effect of DEDA on infarct volume (measured in six serial coronal sections arranged from cranial to caudal regions) and (C) Effect of DEDA on neurologic score. Data for infarct volume (n = 5) are presented as means ± SD. Data for neurological deficit (n = 5) are presented as individual data points. ** p < 0.01 vs. vehicle (Veh).