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Table 4 Odds ratios of Alzheimer's disease for two IL6 and IL10 SNPs, stratified by each other

From: Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease

Odds ratio of AD for :- In the subset :- Numbers   Adjusted* odds ratio of AD (95% CI, p)
   Controls AD cases  
IL6 IL10 AA: 2158 AA: 518 0.86 (0.64–1.15, 0.30)
rs2069837 rs1800871 T+ G+: 348 G+: 87  
AA vs G+ IL10 AA: 3099 AA: 724 1.38 (1.06–1.79, 0.02)
  rs1800871 CC G+: 545 G+: 113  
IL10 IL6 CC: 545 CC: 113 0.63 (0.44–0.91, 0.01)
rs1800871 rs2069837 G+ T+: 348 T+: 87  
CC vs T+ IL6 CC: 3099 CC: 724 1.08 (0.93–1.25, 0.32)
  rs2069837 AA T+: 2158 T+: 518  
  1. IL6 and IL10 = the genes for interleukin-6 and interleukin-10, respectively; AD = Alzheimer's disease; CI = confidence interval; G+ and T+ group the genotypes, GA+GG and CT+TT, respectively; APOEε4 = apolipoprotein E ε4.
  2. *All analyses controlled for centre, age, gender and APOEε4 genotype.