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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics

Figure 2

SDS-PAGE of normal rat IgG and IgM used to assess immunoglobulin uptake by Purkinje cells. SDS-PAGE demonstrates IgG bands at 55 kDa and 26 kDa MW and IgM bands of 75 kDa and 25 kDa. These molecular weights are consistent with IgG and IgM heavy and light chains and are labeled with "H" and "L" respectively. In non-reducing gels, both IgG and IgM produced single bands (data not shown). IgG or IgM breakdown fragments were not detected under either reducing or nonreducing conditions.

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