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Table 2 Age dependent increase of complement expression in non-transgenic mouse brain

From: Expression of complement system components during aging and amyloid deposition in APP transgenic mice

 

3 months

SEM

24 months

SEM

p (2 tailed t-test)

increase with age

C1q

28'345

2'339

89'040

4'788

0.0000001

3×

C4

1'113

155

10'042

1'104

0.00003

9×

factor B

224

28

647

92

0.0009

3×

C3

349

38

3'317

114

0.0000000004

9×

C5

68

7

117

11

0.00001

2×

C6

6

-

13

-

-

below limit of quantification

C8a

not detectable

-

not detectable

-

-

-

C8b

41

-

32

-

-

below limit of quantification

C9

not detectable

-

not detectable

-

-

-

Crry

39'007

1'672

48'546

4'156

0.05

1×

MCP

15

3

20

2

-

below limit of quantification

factor H

16'861

1'532

14'756

723

0.24

1×

  1. Values are given as arbitrary units.
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Journal of Neuroinflammation

ISSN: 1742-2094