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Table 4 Protein levels of iNOS, IL-6, IL-1ß and TNF-α in brain tissue after MCAO and treatment with U0126

From: Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway

Brain-tissue
  Control MCAO MCAO + U0126-0 h MCAO + U0126-6 h MCAO + U0126-12 h
iNOS (%) ± s.e.m 100 ± 7 112.8 ± 6 104 ± 3 100.2 ± 5 103 ± 9
IL-6 (%) ± s.e.m 100 ± 4 108 ± 3.4 94 ± 5 95 ± 3.7 102 ± 5.6
IL-1ß (%) ± s.e.m 100 ± 4.7 122 ± 8.6 100 ± 5 100 ± 3 111 ± 3.1
TNF-α ± s.e.m 100 ± 8 119 ± 14 117 ± 10 114 ± 7.6 122 ± 8.9
  1. Values are expressed as percentage of control and given as mean ± s.e.m, n = 5-6,