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Table 4 Protein levels of iNOS, IL-6, IL-1ß and TNF-α in brain tissue after MCAO and treatment with U0126

From: Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway

Brain-tissue

 

Control

MCAO

MCAO + U0126-0 h

MCAO + U0126-6 h

MCAO + U0126-12 h

iNOS (%) ± s.e.m

100 ± 7

112.8 ± 6

104 ± 3

100.2 ± 5

103 ± 9

IL-6 (%) ± s.e.m

100 ± 4

108 ± 3.4

94 ± 5

95 ± 3.7

102 ± 5.6

IL-1ß (%) ± s.e.m

100 ± 4.7

122 ± 8.6

100 ± 5

100 ± 3

111 ± 3.1

TNF-α ± s.e.m

100 ± 8

119 ± 14

117 ± 10

114 ± 7.6

122 ± 8.9

  1. Values are expressed as percentage of control and given as mean ± s.e.m, n = 5-6,