Cultures of Oligodendrocytes derived from COX-2 transgenic mice over-express COX-2. Dispersed wild-type cultures were prepared from wild-type and transgenic mice the over-express COX-2 specifically in oligodendrocytes (generated with the CNPase promoter fused to the human COX-2 gene. The oligodendrocyte marker to Olig-1 appears red and COX-2 appears green. Co-expression of both appears yellow. Magnification bar = 40 μm.