Figure 3

IL-6 significantly increases in rat brain after GD-induced SE. IL-6 concentrations significantly increase in the hippocampus, piriform cortex and thalamus 12 and 24 hours following GD-induced seizure activity. Concentrations of IL-6 peak at 24 hours in the piriform cortex (solid gray line), and at 12 hours in the hippocampus (solid black line) and thalamus (open gray line). ^## p < 0.01 versus vehicle control in hippocampus, ** p < 0.01 versus vehicle control in piriform cortex, ^$$ p < 0.01 versus vehicle control in thalamus.