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Table 1 Clinical and neuroradiological characteristics of patients with neuromyelitis optica and relapsing myelitis.

From: Aquaporin-4 autoantibodies in neuromyelitis optica spectrum disorders: comparison between tissue-based and cell-based indirect immunofluorescence assays

  NMO (n = 18) RM (n = 15)
Female (%) 15 (83%) 15 (100%)
Mean onset age in years (range) 40.1 (18-64) 45.7 (17-70)
Mean duration of follow-up in years (range) 6.8 (2-16) 5.1 (1-12)
Mean number of AM attack (range) 3.1 (2-9) 2.7 (2-5)
Patients with LETM (%) 17 (94%) 12 (80%)
Mean number of ON attacks (range) 1.9 (1-6) not applicable
Mean relapse rate in first 2 years in number of attack per year (range) 1.5 (0.5-4.0) 0.8 (0.3-2.0)
Mean length of MRI T2W hyperintense signal abnormalities in number of vertebral segments (range) 4.9 (1-16) 4.2 (1-10)
Patients with MRI brain lesions compatible with inflammatory demyelination (%) 10 (56%) 6 (40%)
Patients with CSF OCB (%) 3 (17%) 3 (20%)
Patients with other autoimmune disorders or autoantibodies (%) 9 (50%) 7 (47%)
Patients with poor visual outcome (%) 7 (39%) not applicable
Mean EDSS score at latest follow-up (range) 5.9 (2.0-10) 5.4 (1.0-10)
Patients with poor neurological outcome (%) 12 (67%) 10 (67%)
Mortality 2 (11%) 2 (13%)
  1. Abbreviations: n = number of patients, NMO = neuromyelitis optica, AM = acute myelitis, RM = relapsing myelitis, LETM = longitudinally extensive transverse myelitis, MRI = magnetic resonance imaging, CSF = cerebrospinal fluid, OCB = oligoclonal bands, EDSS = Expanded Disability Status Scale.