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Figure 8 | Journal of Neuroinflammation

Figure 8

From: TGFβ signaling in the brain increases with aging and signals to astrocytes and innate immune cells in the weeks after stroke

Figure 8

TGFβ signaling in activated microglia/macrophages increases in the stroke penumbra after stroke. A.) Representative image (40×) showing CD68+ activated microglia and macrophages) co-localized with pSmad2 after stroke. Image is from a young female mouse at day 3 post stroke. See additional file 5 for a 3D projection. B.) CD68 immunoreactivity increases in the first 3 days after stroke with the majority of CD68+ cells co-localizing with pSmad2 (*p < 0.05 compared to sham).

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Journal of Neuroinflammation

ISSN: 1742-2094