Figure 3
From: Gadofluorine M-enhanced MRI shows involvement of circumventricular organs in neuroinflammation
Early Gf enhancement of the choroid plexus. Coronal T1-weighted images are depicted 1 h after Gf injection (left column) and immediately after Gd-DTPA injection (right column). Applying Gf, distinct enhancement of the choroid plexus (arrow heads) and other CVO was evident early after intravenous injection and allowed for a reliable quantitative signal analysis. In contrast, after injection of Gd-DTPA, the disruption of the blood-CSF barrier frequently caused leakage of contrast agent into the CSF (arrows) obscuring the choroid plexus and periventricular lesions.