Figure 3
From: IL-17A is increased in the serum and in spinal cord CD8 and mast cells of ALS patients
IL-17A-positive cells are CD3 cells and mast cells localized in gray matter; CD3 T cells express granzyme B and caspase-3. Immunohistochemistry (A, E) and immunofluorescence (B, C, D). (A) IL-17A-positive cells (indicated by*) in the gray matter; (B) Granzyme B/CD3 (red/green); (C) caspase-3/CD3 (red/green); (D) IL-17A/CD3 (red/green); (E) IL-17A/mast cell tryptase-positive mast cells (red/brown).