Figure 4
From: Absence of IFNγ expression induces neuronal degeneration in the spinal cord of adult mice
Electron photomicrographs of spinal cord motoneurons of IFNγ-KO mice. (A) α-motoneurons in the lesioned side. Boxed area is shown at higher magnification in (B). The cytoplasm and nuclei are more electron dense and cytoplasmatic organelles are disorganized. Note the presence of numerous vacuoles in the perikaryon (asterisk) and the irregular contour of nuclear membrane. (C) α-motoneurons in the contralateral side. (D) Higher magnification shows the cell less electron dense and with some vacuoles in the cytoplasm. T, synaptic terminal; M, mitochondria; RER, rough endoplasmic reticulum, Nu, nucleus; G, golgi apparatus. Scale bar: 5 μm (A and C), 1 μm (B-D).