Effect of ischemia on spleen weight. A, Quantification of spleen weight before (pre) and after (post) ischemia. B, Quantification of spleen weight expressed ratios of spleen to body weight. Pre, control mice, n = 9; 3d-post, 3 days after MCAO, n = 6; 7d-post, 7 days after MCAO, n = 10. Values were expressed as mean ± SEM. ** p < 0.01 and *** p < 0.001 vs pre.